CIRSA Publications

Our research publications in recent years:

2026  
Saiedi M, Thomas L, Thomas M, Stoyanov N, Nochioka K, Kozor R, Hong GR, Chapman I, Perry R, Selvanayagam JB. Differentiating Anderson-Fabry Disease from Other Causes of Left Ventricular Hypertrophy: Novel Insights from Left Atrial Strain Imaging. J Am Soc Echocardiogr. 2026 Feb;39(2):222-225. doi: 10.1016/j.echo.2025.10.009. Epub 2025 Oct 27. PMID: 41161422.

Hillis GS, Walker JSK, Gilbert T, Budgeon CA, French JK, Selvanayagam JB, Dhakshinamurthy VA, Troughton RW, Moragues J, Ihdayhid AR, Ford TJ, Zaman S, Neill J, Adamson PD, Pemberton J, Doherty E, Whalley GA, Sarathy K, Brieger DB, Wong C, Nielsen LH, Maggiore P, Kueh ASH, Somaratne J, Rajwani A, Benatar J, Stewart RAH. Rationale for and design of the REsolution of LEft VENTricular thrombus (RELEVENT) Trial. Am Heart J. 2026 Mar;293:107301. doi: 10.1016/j.ahj.2025.107301. Epub 2025 Nov 17. PMID: 41238094.

Baskaran G, Pinthus JH, Karampatos S, Ng KKH, Garcia CC, Mian R, Pyne L, Brimble S, Klotz LH, Fradet V, Selvanayagam JB, Guha A, Higano CS, Avezum Á, Hajjar LA, Cavalli GD, Valle FH, Duceppe E, Dusilek CDOL, Shayegan B, Piccoli RK, Gomez-Mesa J, Niazi T, Davis MK, Cita Pardo JE, Luke PP, Leong D; RADICAL PC Investigators. Androgen deprivation therapy and kidney function in patients with prostate cancer: an analysis of the RADICAL-PC cohort. Int Urol Nephrol. 2026 Mar 10. doi: 10.1007/s11255-026-05085-5. Epub ahead of print. PMID: 41807888.

2025
Cho SKS, Darby JRT, Williams GK, Holman SL, Rai A, Van Amerom JFP, Fan CP, Macgowan CK, Selvanayagam JB, Morrison JL, Seed M. Post-Myocardial Infarction Remodeling and Hyperkinetic Remote Myocardium in Sheep Measured by Cardiac MRI Feature Tracking. J Magn Reson Imaging. 2025 Mar;61(3):1323-1335. doi: 10.1002/jmri.29496. Epub 2024 Jun 28. PMID: 38940396; PMCID: PMC11803690.

Slater J, Maron DJ, Jones PG, Bangalore S, Reynolds HR, Fu Z, Stone GW, Kirby R, Hochman JS, Spertus JA; ISCHEMIA Research Group. Evaluating the Appropriate Use Criteria for Coronary Revascularization in Stable Ischemic Heart Disease Using Randomized Data From the ISCHEMIA Trial. Circ Cardiovasc Qual Outcomes. 2025 Mar;18(3):e010849. doi: 10.1161/CIRCOUTCOMES.124.010849. Epub 2025 Feb 26. PMID: 40008421; PMCID: PMC11919559.

Egberts BK, Ananthakrishna R, Perry R, Woodman RJ, Sutton A, Pasupathy S, Hecker T, Bromley TA, Yang WS, Karapetis C, Selvanayagam JB. Myocardial Injury Following Immune Checkpoint Inhibitors: An Australian Experience. Heart Lung Circ. 2025 Jun;34(6):596-605. doi: 10.1016/j.hlc.2024.11.018. Epub 2025 Apr 8. PMID: 40204532.

Egberts BK, Perry R, Stevens W, Prior D, Woodman R, Pasupathy S, Proudman S, Selvanayagam JB. Utility of right ventricular free wall systolic strain for prediction of systemic sclerosis associated pulmonary arterial hypertension. Eur Heart J Cardiovasc Imaging. 2025 Jul 31;26(8):1487-1489. doi: 10.1093/ehjci/jeaf181. PMID: 40569887; PMCID: PMC12311157.

Egberts BK, Ananthakrishna R, Shah R, So ACF, Walker J, Pasupathy S, Proudman S, Selvanayagam JB. Characterization of the Left Ventricular Myocardium in Systemic Sclerosis. J Clin Med. 2025 Aug 8;14(16):5627. doi: 10.3390/jcm14165627. PMID: 40869453; PMCID: PMC12386848.

Huded CP, Spertus JA, Jones PG, O'Brien SM, Mark DB, Bangalore S, Stone GW, Williams DO, White HD, Boden WE, Reynolds HR, Hochman JS, Maron DJ; ISCHEMIA Research Group. Health Status Outcomes With Percutaneous Coronary Intervention and Coronary Artery Bypass Grafting in ISCHEMIA. Circulation. 2025 Sep 23;152(12):846-858. doi: 10.1161/CIRCULATIONAHA.125.073591. Epub 2025 Sep 5. PMID: 40910165; PMCID: PMC12492304.

2024

Reynolds HR, Cyr DD, Merz CNB, Shaw LJ, Chaitman BR, Boden WE, Alexander KP, Rosenberg YD, Bangalore S, Stone GW, Held C, Spertus J, Goetschalckx K, Bockeria O, Newman JD, Berger JS, Elghamaz A, Lopes RD, Min JK, Berman DS, Picard MH, Kwong RY, Harrington RA, Thomas B, O'Brien SM, Maron DJ, Hochman JS; ISCHEMIA Research Group. Sex Differences in Revascularization, Treatment Goals, and Outcomes of Patients With Chronic Coronary Disease: Insights From the ISCHEMIA Trial. J Am Heart Assoc. 2024 Mar 5;13(5):e029850. doi: 10.1161/JAHA.122.029850. Epub 2024 Feb 27. PMID: 38410945; PMCID: PMC10944079.

Yang WS, Grover S, Smith E, Selvanayagam JB. A rare case report of type 1 congenital disorders of glycosylation with acute decompensated heart failure and the incidental discovery of congenital disorders of glycosylation associated dilated cardiomyopathy and acute myocarditis. Eur Heart J Case Rep. 2024 Mar 6;8(3):ytae088. doi: 10.1093/ehjcr/ytae088. PMID: 38449779; PMCID: PMC10917471.

Pracoń R, Spertus JA, Broderick S, Bangalore S, Rockhold FW, Ruzyllo W, Demchenko E, Nageh T, Grossman GB, Mavromatis K, Manjunath CN, Smanio PEP, Stone GW, Mancini GBJ, Boden WE, Newman JD, Reynolds HR, Hochman JS, Maron DJ; ISCHEMIA Research Group. Factors Associated With Coronary Angiography Performed Within 6 Months of Randomization to the Conservative Strategy in the ISCHEMIA Trial. Circ Cardiovasc Interv. 2024 Jun;17(6):e013435. doi: 10.1161/CIRCINTERVENTIONS.123.013435. Epub 2024 Apr 17. PMID: 38629312; PMCID: PMC11187765.

Chan K, Wahome E, Tsiachristas A, Antonopoulos AS, Patel P, Lyasheva M, Kingham L, West H, Oikonomou EK, Volpe L, Mavrogiannis MC, Nicol E, Mittal TK, Halborg T, Kotronias RA, Adlam D, Modi B, Rodrigues J, Screaton N, Kardos A, Greenwood JP, Sabharwal N, De Maria GL, Munir S, McAlindon E, Sohan Y, Tomlins P, Siddique M, Kelion A, Shirodaria C, Pugliese F, Petersen SE, Blankstein R, Desai M, Gersh BJ, Achenbach S, Libby P, Neubauer S, Channon KM, Deanfield J, Antoniades C; ORFAN Consortium. Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study. Lancet. 2024 Jun 15;403(10444):2606-2618. doi: 10.1016/S0140-6736(24)00596-8. Epub 2024 May 29. PMID: 38823406.

Ng HS, Meng R, Marin TS, Damarell RA, Buckley E, Selvanayagam JB, Koczwara B. Cardiovascular mortality in people with cancer compared to the general population: A systematic review and meta-analysis. Cancer Med. 2024 Aug;13(15):e70057. doi: 10.1002/cam4.70057. PMID: 39096123; PMCID: PMC11297437.

Muser D, Chahal AA, Selvanayagam JB, Nucifora G. Clinical Applications of Cardiac Magnetic Resonance Parametric Mapping. Diagnostics (Basel). 2024 Aug 20;14(16):1816. doi: 10.3390/diagnostics14161816. PMID: 39202304; PMCID: PMC11353869.

Leong DP, Fradet V, Niazi T, Selvanayagam JB, Sabbagh R, Higano CS, et al. Adiposity and Muscle Strength in Men With Prostate Cancer and Cardiovascular Outcomes. JACC CardioOncology. 2024;6(5):761-771. doi: 10.1016/j.jaccao.2024.07.011.

Marwick TH, Dewar E, Nolan M, Shirazi M, Dias P, Wright L, et al. Strain surveillance during chemotherapy to improve cardiovascular outcomes: the SUCCOUR-MRI trial. European Heart Journal. 2024:ehae574.

Richardson C, Gilbert T, Aslam S, Brookes CL, Singh A, Newby DE, Dweck MR, Stewart RAH, Myles PS, Briffa T, Selvanayagam J, Chow CK, Murphy GJ, Akowuah EF, Lord J, Barber S, Paola ASD, McCann GP, Hillis GS. Rationale and design of the early valve replacement in severe asymptomatic aortic stenosis trial. Am Heart J. 2024 Sep;275:119-127. doi: 10.1016/j.ahj.2024.05.013. Epub 2024 May 30. PMID: 38821453.

Hamilton-Craig C, Grieve SM, Slaughter R, Chen S, Keenan R, Moses D, Younger JF, Selvanayagam JB, Taylor AJ. CSANZ and RANZCR Position Statement on Initial Certification and Maintenance of Recognition for Cardiac Magnetic Resonance Imaging (CMRI). Heart Lung Circ. 2024 Oct;33(10):1427-1431. doi: 10.1016/j.hlc.2024.03.019. Epub 2024 Jul 31. PMID: 39084940.

Selvanayagam JB, Muser D, Nucifora G. The Pursuit of Improved Arrhythmic Risk Stratification in Nonischemic Cardiomyopathy: Are We Getting Any Closer? J Am Coll Cardiol. 2024 Oct 8;84(15):1421-1423. doi: 10.1016/j.jacc.2024.07.038. Epub 2024 Aug 30. PMID: 39217562.

2023

Klimis H, Pinthus JH, Aghel N, Duceppe E, Fradet V, Brown I, Siemens DR, Shayegan B, Klotz L, Luke PP, Niazi T, Lavallee LT, Mousavi N, Hamilton RJ, Chin JL, Gopaul D, Violette PD, Davis MK, Hanna N, Sabbagh R, Ben Zadok OI, Hajjar LA, Kann AG, Mian R, Rangarajan S, Huei Ng KK, Iakobishvili Z, Selvanayagam JB, Avezum A, Leong DP. The Burden of Uncontrolled Cardiovascular Risk Factors in Men With Prostate Cancer: A RADICAL-PC Analysis. JACC CardioOncol. 2023 Jan 17;5(1):70-81. doi: 10.1016/j.jaccao.2022.09.008.

Ananthakrishna R, Rajvi BP, Hancock DE, Kholmurodova F, Woodman RJ, Patil S, Horsfall M, Chew DP, Daril NDM, Selvanayagam JB. Utility of cardiovascular magnetic resonance in patients with stable troponin elevation. Eur Heart J Cardiovasc Imaging. 2023 Jan 23;24(2):192-201. doi: 10.1093/ehjci/jeac215. PMID: 36336838

Xu R, Xu H, Zhang K, Xu H, Liu H, Fu H, Xie L, Xu K, Fu C, Li X, Zhou X, Ananthakrishna R, Selvanayagam JB, Yu L, Cai X, Guo Y. Prevalence and associated factors of myocardial involvement in Duchenne muscular dystrophy patients in the first decade of life. Chin Med J (Engl). 2023 May 5;136(9):1132-1134. doi: 10.1097/CM9.0000000000002385.

Ghezzi ES, Sharman RLS, Selvanayagam JB, Psaltis PJ, Sanders P, Astley JM, Knayfati S, Batra V, Keage HAD. Burden of mood symptoms and disorders in implantable cardioverter defibrillator patients: a systematic review and meta-analysis of 39 954 patients. Europace. 2023 Jun 2;25(6):euad130. doi: 10.1093/europace/euad130.

Stone GW, Ali ZA, O'Brien SM, Rhodes G, Genereux P, Bangalore S, Mavromatis K, Horst J, Dressler O, Poh KK, Nath RK, Moorthy N, Witkowski A, Dwivedi SK, Bockeria O, Chen J, Smanio PEP, Picard MH, Chaitman BR, Berman DS, Shaw LJ, Boden WE, White HD, Fremes SE, Rosenberg Y, Reynolds HR, Spertus JA, Hochman JS, Maron DJ; ISCHEMIA Research Group. Impact of Complete Revascularization in the ISCHEMIA Trial. J Am Coll Cardiol. 2023 Jul 11:S0735-1097(23)06031-X. doi: 10.1016/j.jacc.2023.06.015.

Selvanayagam JB, Pasupathy S. Challenging the Benign Perception: Unveiling the Prognostic Potential of CMR in MINOCA Patients. JACC Cardiovasc Imaging. 2023 Aug 7:S1936-878X(23)00334-0. doi: 10.1016/j.jcmg.2023.06.018.

Arai AE, Schulz-Menger J, Shah DJ, Han Y, Bandettini WP, Abraham A, Woodard PK, Selvanayagam JB, Hamilton-Craig C, Tan RS, Carr J, Teo L, Kramer CM, Wintersperger BJ, Harisinghani MG, Flamm SD, Friedrich MG, Klem I, Raman SV, Haverstock D, Liu Z, Brueggenwerth G, Santiuste M, Berman DS, Pennell DJ. Stress Perfusion Cardiac Magnetic Resonance vs SPECT Imaging for Detection of Coronary Artery Disease. J Am Coll Cardiol. 2023 Nov 7;82(19):1828-1838. doi: 10.1016/j.jacc.2023.08.046. PMID: 37914512.

2022

Rabbat MG, Kwong RY, Heitner JF, Young AA, Shanbhag SM, Petersen SE, Selvanayagam JB, Berry C, Nagel E, Heydari B, Maceira AM, Shenoy C, Dyke C, Bilchick KC; Society for Cardiovascular Magnetic Resonance. The Future of Cardiac Magnetic Resonance Clinical Trials. JACC Cardiovasc Imaging. 2022 Dec;15(12):2127-2138. doi: 10.1016/j.jcmg.2021.07.029. Epub 2021 Dec 15.

Butcher SC, Pio SM, Kong WKF, Singh GK, Ng ACT, Perry R, Sia CH, Poh KK, Almeida AG, González A, Shen M, Yeo TC, Shanks M, Popescu BA, Galian Gay L, Fijałkowski M, Liang M, Tay E, Ajmone Marsan N, Selvanayagam J, Pinto F, Zamorano JL, Pibarot P, Evangelista A, Bax JJ, Delgado V. Left ventricular remodelling in bicuspid aortic valve disease. Eur Heart J Cardiovasc Imaging. 2022 Nov 17;23(12):1669-1679. doi: 10.1093/ehjci/jeab284. PMID: 34966913

Hecht S, Butcher SC, Pio SM, Kong WKF, Singh GK, Ng ACT, Perry R, Poh KK, Almeida AG, González A, Shen M, Yeo TC, Shanks M, Popescu BA, Gay LG, Fijałkowski M, Liang M, Tay E, Marsan NA, Selvanayagam J, Pinto F, Zamorano JL, Evangelista A, Delgado V, Bax JJ, Pibarot P. Impact of Left Ventricular Ejection Fraction on Clinical Outcomes in Bicuspid Aortic Valve Disease. J Am Coll Cardiol. 2022 Sep 13;80(11):1071-1084. doi: 10.1016/j.jacc.2022.06.032. PMID: 36075677

Ananthakrishna R, Sree Raman K, Shah R, Woodman RJ, Walls A, Bradbrook C, Grover S, Selvanayagam JB. Myocardial Oxygenation in Hibernating Myocardium: Insights From Oxygenation-Sensitive Cardiovascular Magnetic Resonance Imaging. JACC Cardiovasc Imaging. 2022 Jul;15(7):1351-1353. doi: 10.1016/j.jcmg.2022.02.013. Epub 2022 May 11. PMID: 35798410

Senior R, Reynolds HR, Min JK, Berman DS, Picard MH, Chaitman BR, Shaw LJ, Page CB, Govindan SC, Lopez-Sendon J, Peteiro J, Wander GS, Drozdz J, Marin-Neto J, Selvanayagam JB, Newman JD, Thuaire C, Christopher J, Jang JJ, Kwong RY, Bangalore S, Stone GW, O'Brien SM, Boden WE, Maron DJ, Hochman JS; ISCHEMIA Research Group. Predictors of Left Main Coronary Artery Disease in the ISCHEMIA Trial, J Am Coll Cardiol. 2022 Feb 22;79(7):651-661. doi: 10.1016/j.jacc.2021.11.052.

Butcher SC, Fortuni F, Kong W, Vollema EM, Prevedello F, Perry R, Ng ACT, Poh KK, Almeida AG, González-Gómez A, Shen M, Yeo TC, Shanks M, Popescu BA, Galian-Gay L, Fijalkowski M, Liang M, Tay E, Ajmone Marsan N, Selvanayagam JB, Pinto FJ, Zamorano J, Pibarot P, Evangelista A, Bax JJ, Delgado V. Prognostic implications of left atrial dilation in aortic regurgitation due to bicuspid aortic valve. Heart. 2022 Jan;108(2):137-144. doi: 10.1136/heartjnl-2020-318907. Epub 2021 Apr 8. PMID: 33833069

2021

Boyle AJ, Schultz C, Selvanayagam JB, Moir S, Kovacs R, Dib N, Zlotnick D, Al-Omary M, Sugito S, Selvarajah A, Collins N, McLachlan G. Calcium/Calmodulin-Dependent Protein Kinase II Delta Inhibition and Ventricular Remodeling After Myocardial Infarction: A Randomized Clinical Trial. JAMA Cardiol. 2021 Jul 1;6(7):762-768. doi: 10.1001/jamacardio.2021.0676. PMID: 33851966

Muser D, Nucifora G, Pieroni M, Castro SA, Casado Arroyo R, Maeda S, Benhayon DA, Liuba I, Sadek M, Magnani S, Enriquez A, Liang JJ, Sassone B, Desjardins B, Dixit S, Deo R, Garcia FC, Callans DJ, Frankel DS, Selvanayagam JB, Marchlinski FE, Santangeli P Prognostic Value of Non-Ischemic Ring-Like Left Ventricular Scar in Patients with Apparently Idiopathic Non-Sustained Ventricular Arrhythmias. Circulation. 2021 Apr 6;143(14):1359-1373. doi: 10.1161/CIRCULATIONAHA.120.047640. Epub 2021 Jan 6. PMID: 33401956

Quah JX, Dharmaprani D, Tiver K, Lahiri A, Hecker T, Perry R, Selvanayagam JB, Joseph MX, McGavigan A, Ganesan A.J Atrial Fibrosis and Substrate Based Characterisation in Atrial Fibrillation. Time to Move Forwards. J Cardiovasc Electrophysiol. 2021 Apr;32(4):1147-1160. doi: 10.1111/jce.14987. Epub 2021 Mar 17. PMID: 33682258

Sree Raman K, Shah R, Stokes M, Walls A, Woodman RJ, Perry R, Walker JG, Proudman S, De Pasquale CG, Celermajer DS, Selvanayagam JB. Right ventricular myocardial deoxygenation in patients with pulmonary artery hypertension. J Cardiovasc Magn Reson. 2021 Mar 8;23(1):22. doi: 10.1186/s12968-020-00694-0.PMID: 33678188

Shah RJ, Tommasi S, Faull R, Gleadle JM, Mangoni AA, Selvanayagam JB. Arginine metabolites as biomarkers of myocardial ischaemia, assessed with cardiac magnetic resonance imaging in chronic kidney disease. Biomolecules. 2021 Mar 11;11(3):416. doi: 10.3390/biom11030416. PMID: 33799818

Zhao L, Zhang C, Tian J, Saiedi M, Ma C, Li N, Fang F, Ma X, Selvanayagam JB Quantification of myocardial deformation in patients with Fabry disease by cardiovascular magnetic resonance feature tracking imaging. J.Cardiovasc Diagn Ther. 2021 Feb;11(1):91-101. doi: 10.21037/cdt-20-897.PMID: 33708481

Jones DR, Chew DP, Horsfall MJ, Sinhal AR, Joseph MX, Baker RA, Bennetts JS, Selvanayagam JB, Russell AE, De Pasquale CG, Lehman SJ. Impact of increased augmentation index and valvuloarterial impedance on symptom recovery after aortic valve replacement for severe aortic stenosis. Int J Cardiol Heart Vasc. 2021 Jan 6;32:100705. doi: 10.1016/j.ijcha.2020.100705. eCollection 2021

Selvanayagam, J.B., Ananthakrishna, R., Shirodaria, C., Channon, K. Timing of cardiovascular magnetic resonance in clinical trials evaluating cardioprotective therapies to reduce infarct size. Int J Cardiol. 2021 Jan 15;323:272-274. doi: 10.1016/j.ijcard.2020.09.013. Epub 2020 Sep 12. PMID: 32931858

2020

Fuller M, Perry R, Saiedi M, Fletcher JM, Selvanayagam JB. Mono-symptomatic Fabry disease in a population with mild-to-moderate left ventricular hypertrophy. Mol Genet Metab Rep. 2020 Dec 10;25:100697. doi: 10.1016/j.ymgmr.2020.100697. eCollection 2020 Dec. PMID: 33335842

Lopes RD, Alexander KP, Stevens SR, Reynolds HR, Stone GW, Piña IL, Rockhold FW, Elghamaz A, Lopez-Sendon JL, Farsky PS, Chernyavskiy AM, Diaz A, Phaneuf D, De Belder MA, Ma YT, Guzman LA, Khouri M, Sionis A, Hausenloy DJ, Doerr R, Selvanayagam JB, Maggioni AP, Hochman JS, Maron DJ. Initial Invasive Versus Conservative Management of Stable Ischemic Heart Disease in Patients With a History of Heart Failure or Left Ventricular Dysfunction: Insights From the ISCHEMIA Trial. Circulation. 2020 Nov 3;142(18):1725-1735

Sree Raman K, Shah R, Stokes M, Walls A, Woodman RJ, Ananthakrishna R, Walker JG, Proudman S, Steele PM, De Pasquale CG, Celermajer DS, Selvanayagam JB. Left  ventricular ischemia in pre-capillary pulmonary hypertension: a cardiovascular magnetic resonance study. Cardiovasc Diagn Ther. 2020 Oct;10(5):1280-1292.

Hausvater A, Smilowitz NR, Li B, Redel-Traub G, Quien M, Qian Y, Zhong J, Nicholson JM, Camastra G, Bière L, Panovský R, Sá M, Gerbaud E, Selvanayagam JB, Al-Mallah MH, Emrich T, Reynolds HR. Myocarditis in Relation to Angiographic Findings in Patients With Provisional Diagnoses of MINOCA. JACC Cardiovasc Imaging. 2020 Sep;13(9):1906-1913. doi: 10.1016/j.jcmg.2020.02.037. Epub 2020 Jul 9. PMID: 32653544

Nucifora G, Selvanayagam JB. Cardiac Magnetic Resonance Late Gadolinium Enhancement Imaging in Arrhythmic Risk Stratification. Heart Lung Circ. 2020 Sep;29(9):1268-1269

Xu H, Hou K, Xu R, Li Z, Fu H, Wen L, Xie L, Liu H, Selvanayagam JB, Zhang N, Yang Z, Yang M, Guo Y. Clinical Characteristics and Risk Factors of Cardiac Involvement in COVID-19. J Am Heart Assoc. 2020 Sep 15;9(18):e016807

Arai AE, Schulz-Menger J, Berman D, Mahrholdt H, Han Y, Bandettini WP, Gutberlet M, Abraham A, Woodard PK, Selvanayagam JB, McCann GP, Hamilton-Craig C, Schoepf UJ, San Tan R, Kramer CM, Friedrich MG, Haverstock D, Liu Z, Brueggenwerth G, Bacher-Stier C, Santiuste M, Pennell DJ; GadaCAD Investigators. Gadobutrol-Enhanced Cardiac Magnetic Resonance Imaging for Detection of Coronary Artery Disease. J Am Coll Cardiol. 2020 Sep 29;76(13):1536-1547

von Lewinski D, Selvanayagam JB, Schatz RA, Jilma B, Kubica J, Povsic TJ, Nix D, Henauer S, Wallner M; REC-DUT-002 study group. Protocol for a phase 2, randomized, double-blind, placebo-controlled, safety and efficacy study of dutogliptin in combination with filgrastim in early recovery post-myocardial infarction": study protocol for a randomized controlled trial. Trials. 2020 Aug 26;21(1):744

Li X, Li J, Lin L, Shen K, Tian Z, Sun J, Zhang C, An J, Jin Z, Vliegenthart R, Selvanayagam JB, Wang Y.  Left and right ventricular myocardial deformation and late gadolinium enhancement: incremental prognostic value in amyloid light-chain amyloidosis.  Cardiovasc Diagn Ther. 2020 Jun;10(3):470-480. doi:  10.21037/cdt-20-181.

Lock MC, Tellam RL, Darby JRT, Soo JY, Brooks DA, Seed M, Selvanayagam JB, Morrison JL. Identification of Novel miRNAs Involved in Cardiac Repair Following Infarction in Fetal and Adolescent Sheep Hearts. Front Physiol. 2020 Jun 10;11:614. doi: 10.3389/fphys.2020.00614. eCollection 2020.

Kong WKF, Vollema EM, Prevedello F, Perry R, Ng ACT, Poh KK, Almeida AG, González A, Shen M, Yeo TC, Shanks M, Popescu BA, Galian Gay L, Fijałkowski M, Liang M, Chen RW, Ajmone Marsan N, Selvanayagam J, Pinto F, Zamorano JL, Pibarot P, Evangelista A, Delgado V, Bax JJ. Prognostic implications of left ventricular global longitudinal strain in patients with bicuspid aortic valve disease and preserved left ventricular ejection fraction. Eur Heart J Cardiovasc Imaging. 2020 Jul 1;21(7):759-767. doi: 10.1093/ehjci/jez252. PMID: 31633159

Muser D, Santangeli P, Castro SA, Casado Arroyo R, Maeda S, Benhayon DA, Liuba I, Liang JJ, Sadek MM, Chahal A, Magnani S, Pieroni M, Santarossa E, Desjardins B, Dixit S, Garcia FC, Callans DJ, Frankel DS, Alavi A, Marchlinski FE, Selvanayagam JB, Nucifora G. Risk Stratification of Patients with Apparently Idiopathic Premature Ventricular Contractions: A Multicenter International CMR Registry. JACC Clin Electrophysiol. 2020 Jun;6(6):722-735. doi: 10.1016/j.jacep.2019.10.015. Epub 2019 Dec 18. PMID: 32553224

Quah J, Dharmaprani D, Lahiri A, Schopp M, Mitchell L, Selvanayagam JB, Perry R, Chahadi F, Tung M, Ahmad W, Stoyanov N, Joseph MX, Singleton C, McGavigan AD, Ganesan AN. Prospective cross-sectional study using Poisson renewal theory to study phase singularity formation and destruction rates in atrial fibrillation (RENEWAL-AF): Study design. J Arrhythm. 2020 Jun 10;36(4):660-667.

Maron DJ, Hochman JS, Reynolds HR, Bangalore S, O’Brien SM, Boden WE, Chaitman BR, Senior R, Lόpez-Sendόn J, Alexander KP, Lopes RD, Shaw LJ, Berger JS, Newman JD, Sidhu MS, Goodman SG, Ruzyllo W, Gosselin G, Maggioni AP, White HD, Bhargava B, Min JK, Mancini GBJ, Berman DS, Picard MH, Kwong RY, Ali ZA, Mark DB, Spertus JA, Krishnan MN, Elghamaz A, Moorthy N, Hueb WA, Demkow M, Mavromatis K, Bockeria O, Peteiro J, Miller TD, Szwed H, Doerr R, Keltai M, Selvanayagam JB, Steg PG, Held C, Kohsaka S, Mavromichalis S, Kirby R, Jeffries NO, Harrell FE Jr, Rockhold FW, Broderick S, Ferguson TB Jr, Williams DO, Harrington RA, Stone GW, Rosenberg Y; ISCHAEMIA Research Group. Initial Invasive or Conservative Strategy for Stable Coronary Disease. N Engl J Med. 2020 Apr 9;382(15):1395-1407. doi: 10.1056/NEJMoa1915922. Epub 2020 Mar 30.

Lock MC, Tellam RL, Darby JRT, Soo JY, Brooks DA, Macgowan CK, Selvanayagam JB, Porrello ER, Seed M, Keller-Wood M, Morrison JL. Differential gene responses 3 days following infarction in the fetal and adolescent sheep heart. Physiol Genomics. 2020 Mar 1;52(3):143-159.

Ye L, Yang ZG, Selvanayagam JB, Luo H, Yang TZ, Perry R, Diao KY, Huang S, Yang MX, Yang P, Jin Y, Guo YK. Myocardial Strain Imaging by Echocardiography for the Prediction of Cardiotoxicity in Chemotherapy-Treated Patients: A Meta-Analysis. JACC Cardiovasc Imaging. 2020 Mar;13(3):881-882. doi:10.1016/j.jcmg.2019.09.013

Perry P, Patil M, Horsfall M, Marx C, Chew D, McGavigan A, Nucifora G, Selvanayagam JB. Advanced echocardiographic imaging for prediction of sudden cardiac death in patients in moderate and severe left ventricular systolic function. JACC Imaging 2020 Feb;13(2 Pt 2):604-612

2019

Perry R, Selvanayagam JB. Echocardiography in Infiltrative Cardiomyopathy. Heart Lung Circ. 2019 Sep; 28(9):1365-1375

Gregory AT, Stanton T, Thomas L, Selvanayagam JB, Robert Denniss A. Echocardiography: Navigating Complexities to Provide Many Useful Applications in Contemporary Clinical Cardiology. Heart Lung Circ. 2019 Sep;28(9):1303-1306

Grover S, Lloyd R, Perry R, Lou PW, Haan E, Yeates L, Woodman R, Atherton JJ, Semsarian C, Selvanayagam JB. Assessment of myocardial oxygenation, strain, and diastology in MYBPC3-related hypertrophic cardiomyopathy: a cardiovascular magnetic resonance and echocardiography study. Eur Heart J Cardiovasc Imaging. 2019 Aug 1;20(8):932-938. doi: 10.1093/ehjci/jey220. PMID: 30668650

Lewis GA, Dodd S, Naish JH, Selvanayagam JB, Dweck MR, Miller CA. Considerations for Clinical Trials Targeting the Myocardial Interstitium. JACC Cardiovasc Imaging. 2019 Nov;12(11 Pt 2):2319-2331. doi: 10.1016/j.jcmg.2019.03.034. Epub 2019 Aug 14.

Shah R, Sree Raman K, Walls A, Woodman RJ, Faull R, Gleadle JM, Selvanayagam JB. Gadolinium-Free Cardiovascular Magnetic Resonance Stress T1 Mapping in Patients With Chronic Kidney Disease. JACC Cardiovasc Imaging. 2019 Oct;12(10):2083-2085. doi: 10.1016/j.jcmg.2019.04.016. Epub 2019 Jun 12.

Perry R, Swan AL, Hecker T, De Pasquale CG, Selvanayagam JB, Joseph MXThe Spectrum of Change in the Elite Athlete’s Heart. J Am Soc Echocardiogr. 2019 Aug;32(8):978-986

Perry R, Shah R, Saiedi M, Patil S, Ganesan A, Linhart A, Selvanayagam JB. The Role of Cardiac Imaging in the Diagnosis and Management of Anderson-Fabry Disease. JACC Cardiovasc Imaging. 2019 Jul;12(7 Pt 1):1230-1242. doi: 10.1016/j.jcmg.2018.11.039. PMID: 31272606

Jones DR, Chew DP, Horsfall MJ, Chuang AM, Sinhal AR, Joseph MX, Baker RA, Bennetts JS, Selvanayagam JB, Lehman SJ. Multidisciplinary transcatheter aortic valve replacement heart team programme improves mortality in aortic stenosis. Open Heart. 2019 Jul 29;6(2):e000983. doi: 10.1136/openhrt-2018-000983. eCollection 2019. PMID: 31413842

Jones DR, Chew DP, Horsfall MJ, Chuang AM, Sinhal AR, Joseph MX, Baker RA, Bennetts JS, Selvanayagam JB, Lehman SJ. Effect of Balloon Aortic Valvuloplasty on Mortality in Patients With Severe Aortic Stenosis Prior to Conservative Treatment and Surgical or Transcatheter Aortic Valve Replacement. Heart Lung Circ. 2020 May;29(5):719-728. doi: 10.1016/j.hlc.2019.06.717. Epub 2019 Jun 25. PMID: 31285152

Nagel E, Greenwood JP, McCann GP, Bettencourt N, Shah AM, Hussain ST, Perera D, Bucciarelli-Ducci C, Paul M, Westwood MA, Marber M, Richter WS, Puntmann VO, Schwenke C, Schulz-Menger J, Das R, Wong J, Hausenloy DJ, Steen H, Berry C; MR-INFORM Investigators. Magnetic Resonance Perfusion or Fractional Flow Reserve in Coronary Disease. N Engl J Med. 2019 Jun 20;380(25);2418-2428

Hochman JS, Reynolds HR, Bangalore S, O’Brien SM, Alexander KP, Senior R, Boden WE, Stone GW, Goodman SG, Lopes RD, Lopez-Sendon J, White HD, Maggioni AP, Shaw LJ, Min JK, Picard MH, Berman DS, Chaitman BR, Mark DB, Spertus JA, Cyr DD, Bhargava B, Ruzyllo W, Wander GS, Chernyavskiy AM, Rosenberg YD, Maron DJ; ISCHEMIA Randomized Clinical Trial. JAMA Cardiol 2019Mar 1;4(3):273-286.

2018

Bangalore S, Maron DJ, Fleg JL, O’Brien SM, Herzog CA, Stone GW, Mark DB, Spertus JA, Alexander KP, Sidhu MS, Chertow GM, Boden WE, Hochman JS; ISCHEMIA-CKD Research Group International Study of Comparative Health Effectiveness with Medical and Invasive Approaches – Chronic Kidney Disease (ISCHEMIA-CKD): Rationale and design. AM Heart J. 2018 Nov;205:42-52

Kimball A, Patil S, Koczwara B, Raman KS, Perry R, Grover S, Selvanayagam J. Late characterisation of cardiac effects following anthracycline and trastuzumab treatment in breast cancer patients. Int J Cardiol. 2018 Jun 15;261:159-161. doi: 10.1016/j.ijcard.2018.03.025. Epub 2018 Mar 8. PMID: 29576422

Ganesan AN, Gunton J, Nucifora G, McGavigan AD, Selvanayagam JB. Impact of Late Gadolinium Enhancement on mortality, sudden death and major adverse cardiovascular events in ischemic and nonischemic cardiomyopathy: A systematic review and meta-analysis. Int J Cardiol. 2018 Mar 1;254:230-237.

Shah R, Gleadle JM, Selvanayagam JB. Predicting Cardiac Prognosis in Asymptomatic Chronic Kidney Disease Patients. JACC Cardiovasc Imaging. 2018 Feb;11(2 Pt 1):286-287.

Sree Raman K, Nucifora G, Selvanayagam JB. Novel Cardiovascular Magnetic Resonance (CMR) Oxygenation Approaches in Understanding Pathophysiology of Cardiac Diseases. Clin Exp Pharmacol Physiol. 2018 May;45(5):475-480. doi: 10.1111/1440-1681.12916. Epub 2018 Feb 19. PMID: 29350784

Shah RJ, Nucifora G, Perry R, Selvanayagam JB. Non-invasive imaging in Cardiac Deposition Diseases. J Magn Reson Imaging. 2018 Jan;47(1):44-59. doi: 10.1002/jmri.25720. Epub 2017 May 2. PMID: 28464380

2017

Nucifora G, Sree Raman K, Muser D, Shah R, Perry R, Awang Ramli KA, Selvanayagam JB. Cardiac magnetic resonance evaluation of left ventricular functional, morphological, and structural features in children and adolescents vs. young adults with isolated left ventricular non-compaction. Int J Cardiol. 2017 Nov 1;246:68-73. doi: 10.1016/j.ijcard.2017.05.100. PMID: 28867022

Duan AQ, Lock MC, Perumal SR, Darby JR, Soo JY, Selvanayagam JB, Macgowan CK, Seed M, Morrison JL. Feasibility of detecting myocardial infarction in the sheep fetus using late gadolinium enhancement CMR imaging. J Cardiovasc Magn Reson. 2017 Sep 13;19(1):69. doi: 10.1186/s12968-017-0383-1. PMID: 28903760

Pasupathy S, Tavella R, Grover S, Raman B, Procter NEK, Du YT, Mahadavan G, Stafford I, Heresztyn T, Holmes A, Zeitz C, Arstall M, Selvanayagam J, Horowitz JD, Beltrame JF. Early use of N-Acetylcysteine (NAC) with Nitrate Therapy in Patients Undergoing Primary Percutaneous Coronary Intervention for ST-Segment Elevation Myocardial Infarction Reduces Myocardial Infarct Size (The NACIAM Trial). Circulation. 2017 Sep 5;136(10):894-903. doi: 10.1161/CIRCULATIONAHA.117.027575. Epub 2017 Jun 20. PMID: 28634219 Clinical Trial.

Muser D, Tioni C, Shah R, Selvanayagam JB, Nucifora G. Prevalence, Correlates, and Prognostic Relevance of Myocardial Mechanical Dispersion as Assessed by Feature-Tracking Cardiac Magnetic Resonance After a First ST-Segment Elevation Myocardial Infarction. Am J Cardiol. 2017 Aug 15;120(4):527-533. doi: 10.1016/j.amjcard.2017.05.019. Epub 2017 May 30. PMID: 28648394

Selvanayagam JB, Hartshorne T, Billot L, Grover S, Hillis GS, Jung W, Krum H, Prasad S, McGavigan AD. Cardiovascular magnetic resonance-GUIDEd management of mild to moderate left ventricular systolic dysfunction (CMR GUIDE): Study protocol for a randomized controlled trial. Ann Noninvasive Electrocardiol. 2017 Jul;22(4):e12420. doi: 10.1111/anec.12420. Epub 2017 Jan 24. PMID: 28117536

Nucifora G, Tantiongco JP, Crouch G, Bennetts J, Sinhal A, Tully PJ, Bradbrook C, Baker RA, Selvanayagam JB. Changes of left ventricular mechanics after trans-catheter aortic valve implantation and surgical aortic valve replacement for severe aortic stenosis: A tissue-tracking cardiac magnetic resonance study. Int J Cardiol. 2017 Feb 1;228:184-190. doi: 10.1016/j.ijcard.2016.11.200. Epub 2016 Nov 9. PMID: 27865184

Other previous highlight publications

Grover S, Bell G, Lincoff M, Jeorg L, Madsen PL, Huang S, Leow S, Figtree G, Chakrabarty A, Leong DP, Woodman RJ, Selvanayagam JB. Utility of CMR Markers of Myocardial Injury in Predicting LV Functional Recovery: Results from PROTECTION AMI CMR Sub-study. Heart Lung Circ. 2015 Sep;24(9):891-7. doi: 10.1016/j.hlc.2015.03.001. Epub 2015 Mar 24. PMID: 25846255

Leong DP, Penhall A, Perry R, Shirazi M, Altman M, Chong D, Bradley J, Joseph MX, Selvanayagam JB. Speckle-tracking strain of the left atrium: a transoesophageal echocardiographic validation study. Eur Heart J Cardiovasc Imaging. 2013 Sep;14(9):898-905. doi: 10.1093/ehjci/jes323. Epub 2013 Jan 11. PMID: 23313918